e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521
Syntheses of 4, 5-Diaryl-1, 2, 3-thiadiazoles 1
…, L Navidpour, M Amini, A Shafiee
Index: Karimi, Lila; Navidpour, Latifeh; Amini, Mohsen; Shafiee, Abbas Phosphorus, Sulfur and Silicon and the Related Elements, 2005 , vol. 180, # 7 p. 1593 - 1600
Abstract Reaction of thionyl chloride with semicarbazones of 1-(4-methylsulfonylphenyl)-2-(4- substituted pheny) lethanone gave 4-(4-methylsulfonylphenyl)-5-(4-substituted) pheny-1, 2, 3-thiadiazoles 5. Compounds 5-phenyl-4-(substitutedphenyl)-1, 2, 3-thiadiazoles 14 were similarly prepared. Chlorosulfonation of the latter followed by ammonia gave the desired compounds 5-(4-aminosulfonylphenyl)-4-(substituted) phenyl-1, 2, 3-thiadiazoles 6.