Tetrahedron letters

A mechanistic study of the chromium (II)-mediated transformations of trichloromethyl alkyls and carbinols: evidence for carbene, carbyne, and carbenoid intermediates

R Bejot, S Tisserand, DR Li, JR Falck, C Mioskowski

Index: Bejot, Romain; Tisserand, Steve; Li, De Run; Falck; Mioskowski, Charles Tetrahedron Letters, 2007 , vol. 48, # 22 p. 3855 - 3858

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Citation Number: 11

Abstract

Using CrCl2 in THF at room temperature, trichloromethyl carbinols and trichloromethylalkanes are readily transformed to the highly reactive α-chlorocarbenes, carbynes and α-chloro-α-chromium (III) vinylidene carbenoids. A mechanistic study is carried out to determine the nature of the intermediates.