Synthetic communications

Application of Sulfinyl bis (2, 4??dihydroxythiobenzoyl) in the Synthesis of N??Substituted 2??Amino??5??(2, 4??dihydroxyphenyl)??1, 3, 4??thiadiazoles

J Matysiak, A Niewiadomy

Index: Matysiak, Joanna; Niewiadomy, Andrzej Synthetic Communications, 2006 , vol. 36, # 11 p. 1621 - 1630

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Citation Number: 32

Abstract

Abstract One??stage synthesis of N??substituted 2??amino??5??(2, 4??dihydroxyphenyl)??1, 3, 4?? thiadiazoles is described. The compounds were prepared by the reaction of the sulfinyl bis (2, 4??dihydroxythiobenzoyl)(STB) with 4??substituted 3??thiosemicarbazides. STB was obtained from 2, 4??dihydroxybenzenecarbodithioic acid and thionyl dichloride. The structure of compounds was confirmed by IR, 1H NMR, 13C NMR, and EI??MS data.