A number of 4-aminoquinoline derivatives, especially those with a 7-chlorine atom, have been found to possess marked antimalarial acti~ ity.~.'The usual procedure for their preparathn involves treatment of the requisite 4-chloroquinoline with the proper diamine side-chain. The synthesis of 4-hydroxyquinolines, necessary as intermediates in this type of preparation, has been discussed in a recent series of papers from this Laboratory. 6 The ...
![Propanedinitrile,2-[[(3-chlorophenyl)amino]methylene]- Structure](https://image.chemsrc.com/caspic/245/6288-52-4.png)
