Hansch analysis of veratric acid derivatives as antimicrobial agents

B Narasimhan, S Ohlan, R Ohlan, V Judge…

Index: Narasimhan, Balasubramanian; Ohlan, Sucheta; Ohlan, Ruchita; Judge, Vikramjeet; Narang, Rakesh European Journal of Medicinal Chemistry, 2009 , vol. 44, # 2 p. 689 - 700

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Citation Number: 32

Abstract

The synthesis, characterization and antimicrobial evaluation of a new series of veratric acid derivatives are presented. Preliminary in vitro antimicrobial activity of the title compounds was assessed against a panel of microorganisms including Gram-positive and Gram- negative bacteria and fungi. Some of the veratric acid derivatives exhibited significant in vitro antimicrobial activity. QSAR investigation applied to find a correlation between different ...