Syntheses of the amathamides A and B ((2S)-N-[(E and Z)-2 (2, 4-dibromo-5- methoxyphenylethenyl]-1-methyl-2-pyrrolinecarboxamides), new alkaloids isolated from the Tasmanian marine bryozoan Amathia wilsoni, were accomplished by a sequence of reactions starting from 3-hydroxybenzaldehyde.