A remarkably simple preparation of (trifluoromethyl) cadmium and-zinc reagents directly from difluorodihalomethanes

DJ Burton, DM Wiemers

Index: Burton, Donald J.; Wiemers, Denise M. Journal of the American Chemical Society, 1985 , vol. 107, p. 5014 - 5015

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Citation Number: 151

Abstract

Bioactive drugs and agricultural chemicals that contain a trifluoromethyl group have been the subjects of increased research activity in recent years. 2 Concomitant with these applications has been renewed vigor in the design of a cheaper and more efficient synthetic methodology for the introduction of the trifluoromethyl group into organic compounds. An adjunct of this strategy has been a revival in the preparation of trifluoromethyl ...