Tetrahedron Letters

Condition-controlled selective synthesis of coumarins and flavones from 3-(2-hydroxyphenyl) propiolates and iodine

S Cai, Y Shen, P Lu, Y Wang

Index: Cai, Shuying; Shen, Yang; Lu, Ping; Wang, Yanguang Tetrahedron Letters, 2011 , vol. 52, # 32 p. 4164 - 4167

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Citation Number: 4

Abstract

Both 2H-chromen-2-ones (coumarins) and 4H-chromen-4-ones (flavones) 1 are of paramount importance because of their bioactivities in nature. 2 Coumarins are widely used in the pharmaceutical company as precursors in the synthesis of a variety of anticoagulant pharmaceuticals and some even more efficient rodenticides that work by the same anticoagulant mechanism. Coumarins also possess clinical values in the treatment of lymphedema. 3 Industry of flavones has ...