The Journal of organic chemistry

N-Silyloxaziridines: Synthesis and Use for Electrophilic Amination

N Richy, M Ghoraf, J Vidal

Index: Richy, Nicolas; Ghoraf, Mohammed; Vidal, Joelle Journal of Organic Chemistry, 2012 , vol. 77, # 23 p. 10972 - 10977

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Citation Number: 4

Abstract

N-Silyloxaziridines were synthesized for the first time. Their tert-butyldiphenylsilyl (TBDPS) derivatives were stable reagents that were prepared on a multigram scale in three steps and in 44% overall yield from the corresponding benzylamines. They were mild electrophilic aminating reagents that reacted at room temperature with diversely substituted primary and secondary amines to produce N-monoalkyl or N, N-dialkyl benzaldehyde hydrazones in ...