e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521
Tetrahedron
Photoinduced vinylcyclopropane-cyclopentene rearrangement: A methodology for chiral bicyclo [3.2. 0] heptenes. Formai syntheses of (±)-grandisol and naturally …
The problem of achieving reaction selectivity in cis-alkyl vinylcyclopropanes in favour of their rearrangement to cyclopentenes, obviating the competing low energy process of the [1, 5](homo) sigmatropic hydrogen shift, is addressed. It has been demonstrated that the readily available bicyclo [4.1. 0] heptenes derived from (+)-Δ3-carene.(1), upon photosensitized irradiation, are conveniently transformed into chiral cis-bicyclo [3.2. 0] heptenes. The ...