There has been a recent resurgence of interest in transition metal-catalysed amination reactions and it is now possible to effect efficient and highly selective 1,5- or 1,6-CH insertions under mild conditions using carbamate or sulfamate ester precursors respectively. 1 Du Bois' recent total syntheses of tetrodotoxin and manzacidin A 2 serve as excellent illustrations of what can be achieved using this new synthetic tool. Aziridination has also developed at a fast pace, with ...
