Studies examining the relationship between the chemical structure of protoxin II and its activity on voltage gated sodium channels

JH Park, KP Carlin, G Wu, VI Ilyin…

Index: Kers, Inger; MacSari, Istvan; Csjernyik, Gabor; Nyloef, Martin; Skogholm, Karin; Sandberg, Lars; Minidis, Alexander; Bueters, Tjerk; Malmborg, Jonas; Eriksson, Anders B.; Lund, Per-Eric; Venyike, Elisabet; Luo, Lei; Nystroem, Jan-Erik; Besidski, Yevgeni Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 19 p. 6108 - 6115

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Citation Number: 9

Abstract

... Waters). Two gradients were used: (i) 10–60% B over 30 min with a flow rate of 1 mL/min; (ii) 10–60% B over 15 min with a flow rate of 1 mL/min. Buffer A was 0.1% TFA in water, and buffer B was 0.1% TFA in acetonitrile. The ...