Abstract The use of a recyclable silica-supported palladium catalyst in Sonogashira couplings and indole syntheses using a range of functionalised substrates is described. The catalyst is shown to be both robust and versatile, effecting the synthesis of 2-phenylindole in quantitative yield without the need for N-protection, a copper cocatalyst, a base, or a solvent.
![5-[(2-aminophenyl)ethynyl]indole Structure](https://image.chemsrc.com/caspic/218/958742-77-3.png)
