e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521
Metathesis studies to cyclic enol phosphonamidates
…, MD McReynolds, CE Schroeder, PR Hanson
Index: Sieck, Stephen R.; McReynolds, Matthew D.; Schroeder, Chad E.; Hanson, Paul R. Journal of Organometallic Chemistry, 2006 , vol. 691, # 24-25 p. 5307 - 5311
The development of cyclic, six membered enol phosphonamidates utilizing the ring-closing metathesis (RCM) reaction is discussed. Phosphonamidic monochloridates are generated and further functionalized to an array of acyclic, enol phosphonamidates. Subsequent metathesis affords both desired RCM product and corresponding cross metathesis (CM) dimer. Efforts to optimize formation of desired RCM product, while minimizing CM products ...