6 but as an oil, which was converted to perchlorate 2b (82%). Recrystallization of crude 2b from ethanol gave a product of high purity, which produced consistent biological screening data. Alcohol 3a was prepared (81%) by the addition of 2 equiv of phenylmagnesium bromide to ketone 1 in ether in approximately 2 h. Recrystallization of crude 3a from ethanol gave only one pure isomer. Consequently, the addition appeared to be very ...
