Tetrahedron letters

A convenient synthesis of β-alkynylpropionic acids from β-propiolactones. Synthesis of 4, 4, 5, 5-tetradehydro-9 (O)-methano-Δ 6 (9α)-PGI 1

M Shinoda, K Iseki, T Oguri, Y Hayasi, S Yamada…

Index: Shinoda; Iseki; Oguri; et al. Tetrahedron Letters, 1986 , vol. 27, # 1 p. 87 - 90

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Citation Number: 15

Abstract

Download full text in PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... A new prostacyclin analog, 4,4,5,5-tetradehydro-9(0)-methano-gD 6 (9α)-PGI, has been synthesized by utilizing the regiocontrolled cleavage of the β-propiolactone uith the dialkylaluminum acetylide. ... PMR(CDCl 3 )δ(ppm): 5.87 (broads, 1H), 4.5~4.7(m, 1H), 3.70(s, 3H), 2.60( ...