Archiv der Pharmazie

Synthesis of Furo??salicylanilides and Their Heterocyclic Derivatives with Anticipated Molluscicidal Activity

GS Hassan, GH Hegazy, HM Safwat

Index: Hassan, Ghaneya Sayed; Hegazy, Gehan Hegazy; Safwat, Hany Mohamed Archiv der Pharmazie, 2006 , vol. 339, # 8 p. 448 - 455

Full Text: HTML

Citation Number: 13

Abstract

Abstract The synthesis of new furo-salicylanilides and their heterocyclic derivatives is described. Twenty-three compounds were screened for their molluscicidal activity against Biomphalaria alexandrina snails, the intermediate host of Schistosoma mansoni. Five of the tested compounds showed no activity, while eighteen compounds showed strong to moderate activity using bayluscide as a reference.