Copper (II)??Catalyzed meta??Selective Direct Arylation of α??Aryl Carbonyl Compounds

HA Duong, RE Gilligan, ML Cooke…

Index: Duong, Hung A.; Gilligan, Ruth E.; Cooke, Michael L.; Phipps, Robert J.; Gaunt, Matthew J. Angewandte Chemie - International Edition, 2011 , vol. 50, # 2 p. 463 - 466

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Citation Number: 165

Abstract

Substituted arenes dominate the properties of many natural products, medicines, and materials.[1] Therefore, the development of new methods for direct and selective aromatic functionalization is a persistent challenge for synthetic chemists.[2] A particularly important class of substituted aromatic compounds is the α-aryl carbonyl structure. These molecules represent broadly useful starting materials for complex molecule synthesis, and the basic ...