Molecular Nutrition & Food Research 2018-04-03

Sugary Kefir Strain Lactobacillus mali APS1 Ameliorated Hepatic Steatosis by Regulation of SIRT‐1/Nrf‐2 and Gut Microbiota in Rats

Yung‐Tsung Chen; Yu‐Chun Lin; Jin‐Seng Lin; Ning‐Sun Yang; Ming‐Ju Chen

Index: 10.1002/mnfr.201700903

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Abstract

Non‐alcoholic fatty liver disease (NAFLD) is a common disease that is concomitant with obesity, resulting in increased mortality. To date, the efficiency of NAFLD treatment still needs to be improved. Therefore, we aimed to evaluate the effect of Lactobacillus mali APS1, which was isolated from sugary kefir, on hepatic steatosis in rats fed a high‐fat diet (HFD).