Tetrahedron letters

Radical cyclizations to quinolone and isoquinolone systems under oxidative and reductive conditions

…, LD Miranda, R Cruz-Almanza, JM Muchowski

Index: Osornio, Yazmin M.; Miranda, Luis D.; Cruz-Almanza, Raymundo; Muchowski, Joseph M. Tetrahedron Letters, 2004 , vol. 45, # 13 p. 2855 - 2858

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Citation Number: 21

Abstract

Radical cyclizations to quinolone and isoquinolone systems under Fenton-type and n- Bu3SnH-mediated conditions are described. For N-iodoalkylquinolones, ca. 3: 1 mixtures of oxidative cyclization products at C-2, and unexpectedly at C-8, were obtained under both conditions. Five-or six-membered oxidative cyclization products were obtained from N- iodoalkylisoquinolones under Fenton-type conditions, whereas n-Bu3SnH-mediated ...