Synthesis and carbon??13 NMR study of 2??benzyl, 2??methyl, 2??aryloctahydropyrrolo [3, 4??c] pyrroles and the 1, 2, 3, 5??tetrahydropyrrolo [3, 4??c] pyrrole ring system

CJ Ohnmacht, CW Draper, RF Dedinas…

Index: Ohnmacht, Cyrus J.; Draper, Clyde W.; Dedinas, Robert F.; Loftus, Philip; Wong, J. J. Journal of Heterocyclic Chemistry, 1983 , vol. 20, p. 321 - 329

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Citation Number: 8

Abstract

Abstract 2-Benzyl, 2-phenyl, 2-(3-methoxyphenyl) and 2-(3-trifluoromethylphenyl) octahydropyrrolo [3, 4-c] pyrrole (9a, 9b, 9c, and 9d, respectively) were prepared in five steps from 1-benzylpyrrole-3, 4-dicarboxylic acid (2). 2-Methyloctahydropyrrolo [3, 4-c] pyrrole (9′ a) was prepared analogously in six steps from 1-methylpyrrole-3, 4-dicarboxylic acid (3). Diborane reduction of 1-benzyl-N-methyl-1H-pyrrole-3, 4-dicarboximide (7′ a) ...