Synthesis and biological activity of allylpyrimidines and their derivatives

RG Melik-Ogandzhanyan, GG Danagulyan…

Index: Melik-Ogandzhanyan, R. G.; Danagulyan, G. G.; Fagradyan, S. A.; Mirozoyan, V. S.; Okhikyan, V. M.; et al. Pharmaceutical Chemistry Journal, 1983 , vol. 17, # 3 p. 190 - 195 Khimiko-Farmatsevticheskii Zhurnal, 1983 , vol. 17, # 3 p. 299 - 303

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Abstract

The PM_R spectra of the allylpyrimidines (I-IV) showed, in addition to signals for the methyl and substituted amino groups, signals assigned to the allyl group, appearing as a quadruplet for the methylene group (3.35 ppm, JI, 2 5 Hz, JI, 3 1 Hz), and signals for the vinyl protons (quadruplet for= CH2 at 5 ppm and a multiplet for the methine group at 5.5-6.0 ppm).