Advanced Healthcare Materials 2018-02-21

Human Tissue Models: Engineering 3D Hydrogels for Personalized In Vitro Human Tissue Models (Adv. Healthcare Mater. 4/2018)

Chya-Yan Liaw, Shen Ji, Murat Guvendiren

Index: 10.1002/adhm.201870021

Full Text: HTML

Abstract

The use of hydrogel scaffolds for developing in vitro patient-specific tissue and organ models using human-derived cells is a powerful platform for studying the mechanism of disease initiation and progression, screening of potential drug candidates, and ultimately, the regeneration of fully functional tissues and organs. In article number 1701165, Murat Guvendiren and co-workers review the current developments in hydrogel-based in vitro tissue models and fabrication techniques, with particular focus on liver and cancer tissues.