We constructed a series of novel chiral molecular face-rotating polyhedra (FRP) from two 10,15-dihydro-5H-diindolo[3,2-a:3',2'-c]carbazole (triazatruxene) derivatives and trans-1,2-cyclohexane diamine, and investigated how facial interactions and the positions of substituents determine the diastereoselectivity and geometry of the molecular FRP.