Saccharin derivatives II. Synthesis of 4??nitrosaccharin and related compounds

GH Hamor

Index: Hamor,G.H. Journal of the American Pharmaceutical Association, Scientific Edition, 1960 , vol. 49, p. 280 - 283

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Citation Number: 8

Abstract

Abstract Five new saccharin derivatives were prepared: 4-nitrosaccharin, 4-aminosaccharin, 4-acetamidosaccharin, 2-ethyl-4-nitrosaccharin, and 2-n-propyl-4-nitrosaccharin. Attempts to prepare 5-nitrosaccharin, using procedures described in the literature, gave instead a mixture of two nitrosaccharins, which was shown to consist of the known 6-nitrosaccharin plus 4-nitrosaccharin identical to the above compound. The new saccharin derivatives ...