Heterocycles

Mononuclear heterocyclic rearrangement

DA Berry, TC Chien, LB Townsend

Index: Berry, David A.; Chien, Tun-Cheng; Townsend, Leroy B. Heterocycles, 2004 , vol. 63, # 11 p. 2475 - 2494

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Citation Number: 12

Abstract

Abstract The formation of [5: 5] bicyclic heterocyclic ring systems containing [c] pyrazoles, ie imidazo [4, 5-c] pyrazole, pyrazolo [3, 4-c] pyrazole, pyrrolo-[2, 3-c] pyrazole, and pyrazolo [3, 4-d][1, 2, 3] triazole, was accomplished by mononuclear heterocyclic rearrangement (MHR). The core pyrazole ring was formed based on a NN bond formation strategy. The ring transformation of 5-substituted 3-(2-aminoaryl)-1, 2, 4-oxadiazoles (14, 15a-b, 16b and 33 ...