The Journal of Organic Chemistry

A new synthesis of medium, and large membered lactones via denitration of nitro-lactones

N Ono, H Miyake, A Kaji

Index: Ono, Noboru; Miyake, Hideyoshi; Kaji, Aritsune Journal of Organic Chemistry, 1984 , vol. 49, # 25 p. 4997 - 4999

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Citation Number: 47

Abstract

Method B. 6-Bromo-l-(chloromethyl)-2-methoxynaphthalene (4)(5.7 g, 0.02 mol) was dissolved in 125 mL of warm ethyl acetate. Triethylamine (5 mL) and 5% Pd/C (500 mg) were added, and the mixture was hydrogenated as in method A. The reaction was worked up as above and the white crystals of 8 (3.3 g, 96%); mp 35-7" C, were identical by IR and NMR with the product prepared by method A.