Chemical Society Reviews 2018-03-20

Advances in liquid metals for biomedical applications

Junjie Yan, Yue Lu, Guojun Chen, Min Yang, Zhen Gu

Index: 10.1039/C7CS00309A

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Abstract

10.1039/C7CS00309A picture

To date, liquid metals have been widely applied in many fields such as electronics, mechanical engineering and energy. In the last decade, with a better understanding of the physicochemical properties such as low viscosity, good fluidity, high thermal/electrical conductivity and good biocompatibility, gallium and gallium-based low-melting-point (near or below physiological temperature) alloys have attracted considerable attention in bio-related applications. This tutorial review introduces the common performances of liquid metals, highlights their featured properties, as well as summarizes various state-of-the-art bio-applications involving carriers for drug delivery, molecular imaging, cancer therapy and biomedical devices. Challenges for the clinical translation of liquid metals are also discussed.