Abstract 7-Alkanoyloxy-3, 7-dimefhyl-7, 8-dihydro-6H-isochromene-6, 8-diones 12-15 were synthesized in 69-16% yields from the reaction of 2, 4-dihydroxy-3-methyl-6-(2-oxopropyl) benzaldehyde 11 with p-toluenesulfonic acid in various carboxylic acids such as acetic acid, propionic acid, butyric acid and heptanoic acid followed by oxidation with lead tetraacetate. On the other hand,(±)-daldinin A 5 (oleate) was not obtained using oleic acid as a medium ...
[Moormann, Alan E.; Pitzele, Barnett S.; Jones, P. H.; Gullikson, Gary W.; Albin, David; et al. Journal of Medicinal Chemistry, 1990 , vol. 33, # 2 p. 614 - 626]
