Small Methods 2018-03-09

Single-Cell Sampling: Sampling from Single Cells (Small Methods 3/2018)

Paolo Actis

Index: 10.1002/smtd.201770124

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Abstract

The cell is the fundamental unit of life. In article number 1700300, Paolo Actis reviews nanoprobe-based methods for extracting the content of living cells without affecting their viability, and paints a picture of the innovative methods that are introducing single-cell biopsy as a way to repeatedly interrogate single living cells over time, thus enabling the dynamic study of the cell's genetic make-up, rather than a snapshot at a particular point in time.