Tetrahedron letters

An efficient modification of the Hofmann rearrangement: synthesis of methyl carbamates

P Gogoi, D Konwar

Index: Gogoi, Pranjal; Konwar, Dilip Tetrahedron Letters, 2007 , vol. 48, # 4 p. 531 - 533

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Citation Number: 23

Abstract

The use of solid-supported reagents has become ubiquitous due to their unique properties, such as enhanced reactivity, selectivity, mild conditions and avoidance of cumbersome aqueous work-ups and a decrease in solvent waste. 10 For example, KF/Al 2 O 3 is known to be a useful and interesting solid-supported strong base, which has led to it replacing organic bases in a variety of reactions. 11 On the other hand, sodium hypochlorite is an inexpensive, ...