Tetrahedron Letters

A new synthesis of dl-muscopyridine based on the regioselective cyclopentenone annulation

H Saimoto, T Hiyama, H Nozaki

Index: Saimoto, Hiroyuki; Hiyama, Tamejiro; Nozaki, Hitosi Tetrahedron Letters, 1980 , vol. 21, p. 3897 - 3898

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Citation Number: 14

Abstract

Abstract Sulphuric acid catalyzed ring closure of propargyl alcohol dianion adduct of 2- cyclododecenone gives bicyclo [10.3. 0] pentadec-1 (12), 2-dien-13-one. 1, 6-Conjugate addition of methyl group followed by ring-expansion and aromatization affords the title compounds.