The sodium tungstate catalyzed oxidation of 1, 2, 3, 4-tetrahydroquinolines (1) with 30% aqueous hydrogen peroxide solution in methanol gives l-hydroxy-3, 4-dihydroquinolin-2 (1~- ones(2), which are important biologically active compounds, in good to excellent yields. The cyclic hydroxamic acid 7 is also obtained in good yield. Since reduction of 2 thus obtained gives 3, 4-dihydroquinolin-2 (lH)-ones (4), the present reaction provides a convenient ...
[Murahashi, Shun-Ichi; Oda, Tetsuya; Sugahara, Toshiaki; Masui, Yoshiyuki Journal of the Chemical Society, Chemical Communications, 1987 , # 19 p. 1471 - 1472]
