Hydrolysis of Phostonates1, 2

A Eberhard, FH Westheimer

Index: Eberhard,A.; Westheimer,F.H. Journal of the American Chemical Society, 1965 , vol. 87, # 2 p. 253 - 260

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Citation Number: 56

Abstract

Most of the reactions which establish the structures and interrelationships of these compounds are summarized in Charts 1-111. Supplementary data are available elsewhere. The percentages of cleavage at the P-0 and C-0 bonds were determined for all three compounds by conducting the hydrolyses in water enriched in'* O and analyzing the products for IKO. This procedure is straightforward for the phosphonate ester, but the ...