Identification and specificity studies of small-molecule ligands for SH3 protein domains

SR Inglis, C Stojkoski, KM Branson…

Index: Watanabe, Tokuhiro; Kikuchi, Etsuko; Tamura, Wataru; Akita, Yasuo; Tsutsui, Mayumi; Ohta, Akihiro Heterocycles, 1980 , vol. 14, # 3 p. 287 - 290

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Citation Number: 62

Abstract

... Volume: Page: ... Tec Kinase SH3 domain as a model system for structure-based ligand design, we have identified several simple heterocyclic compounds that ... Using the solution structure of the mouse Tec IV SH3 domain, 13,14 in silico screens of small molecule ...