SN2′ Boron??Mediated Mitsunobu Reactions–A New One??Pot Three??Component Synthesis of Substituted Enamides and Enol Benzoates

F Berrée, N Gernigon, A Hercouet…

Index: Berree, Fabienne; Gernigon, Nicolas; Hercouet, Alain; Chia, Hui Lin; Carboni, Bertrand European Journal of Organic Chemistry, 2009 , # 3 p. 329 - 333

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Citation Number: 14

Abstract

Abstract The conversion of (3-hydroxy-1-propen-1-yl) boronates to substituted enamides and enol benzoates is readily achieved in a one-pot procedure consisting of a regiocontrolled Mitsunobu reaction with convenient nucleophiles, followed by allylboration of aldehydes.(© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2009)