Novel Regiocontrolled Protection of 1, 2-and 1, 3-Diols via Mild Cleavage of Methylene Acetals

H Fujioka, K Senami, O Kubo, K Yahata…

Index: Fujioka, Hiromichi; Kubo, Ozora; Okamoto, Kazuhisa; Senami, Kento; Okitsu, Takashi; Ohnaka, Takuya; Sawama, Yoshinari; Kita, Yasuyuki Heterocycles, 2009 , vol. 77, # 2 p. 1089 - 1103

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Citation Number: 10

Abstract

The regiocontrolled protection of unsymmetrical 1, 2-and 1, 3-diols has been developed. Different types of protected diols are available from the methylene acetal in a one-pot procedure. Highly regioselective protection of diols with a silyl group at the less hindered

~85%

~83%

~84%

~99%

~90%

~83%

~84%

~65%

The reaction of acetal-type protective groups in combination...

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Total synthesis of cyclostellettamine C, a bispyridinium mac...

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Facile and highly selective monoacylation of symmetric diols...

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