Tetrahedron Letters

Novel synthesis of perfluoroalkylated heterocyclic compounds from α-chlorostyrenes via perfluoroalkylated α, β-unsaturated ketones

M Ohkoshi, M Yoshida, H Matsuyama, M Iyoda

Index: Ohkoshi, Masanori; Yoshida, Masato; Matsuyama, Haruo; Iyoda, Masahiko Tetrahedron Letters, 2001 , vol. 42, # 1 p. 33 - 36

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Citation Number: 14

Abstract

Development of an efficient method for the synthesis of perfluoroalkylated heterocyclic compounds is currently an important subject, especially in agrochemical and pharmaceutical fields, 1 because the fluoroalkylated heterocyclic compounds have high potential as herbicides, fungicides, drugs and pesticides, etc. 2 Among the various methods, the building-block strategy is the most popular and attractive. In our continuous work on oxygenative perfluoroalkylation of olefins, 3. and ...