Multinuclear Non??Heme Iron Complexes for Double??Strand DNA Cleavage

…, AD de Bruijn, BL Feringa, G Roelfes

Index: Megens, Rik P.; Van Den Berg, Tieme A.; De Bruijn, A. Dowine; Feringa, Ben L.; Roelfes, Gerard Chemistry - A European Journal, 2009 , vol. 15, # 7 p. 1723 - 1733

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Citation Number: 20

Abstract

Abstract Bleomycin mimics: Efficient oxidative double-strand DNA cleavage has been achieved with multinuclear non-heme iron complexes (see scheme). These complexes therefore represent model compounds that mimic the mode of action of the anti-tumor drug bleomycin.