Tetrahedron letters

Enantiospecific construction of the BC-ring system of taxanes

A Srikrishna, DH Dethe, PR Kumar

Index: Srikrishna; Dethe, Dattatraya H.; Kumar, P. Ravi Tetrahedron Letters, 2004 , vol. 45, # 14 p. 2939 - 2942

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Citation Number: 22

Abstract

Two alternative approaches to the BC-ring system of taxanes, suitable for generating both enantiomeric forms of taxanes, starting from the readily and abundantly available monoterpene (R)-carvone employing a ring-closing metathesis reaction as key step, are described.