Tetrahedron Letters

Condensation of propargylic alcohols with 1, 3-dicarbonyl compounds and 4-hydroxycoumarins in ionic liquids (ILs)

G Aridoss, KK Laali

Index: Aridoss, Gopalakrishnan; Laali, Kenneth K. Tetrahedron Letters, 2011 , vol. 52, # 51 p. 6859 - 6864

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Citation Number: 25

Abstract

Propargylic alcohols are activated toward 1, 3-diketones by Lewis or Brønsted acidic ionic liquids (ILs) without an added catalyst, but significantly better conversions are achieved with metallic triflates [in particular Sc (OTf) 3 and Ln (OTf) 3] and bismuth nitrate in imidazolium ILs. The scope of this condensation reaction was investigated with a variety of propargylic alcohols and a host of acyclic and cyclic dicarbonyl compounds. Concomitant ...