The Journal of organic chemistry

Synthesis and evaluation of ketophosph (on) ates as β-lactamase inhibitors

SK Perumal, RF Pratt

Index: Perumal, Senthil K.; Pratt Journal of Organic Chemistry, 2006 , vol. 71, # 13 p. 4778 - 4785

Full Text: HTML

Citation Number: 22

Abstract

A series of amidoketophosph (on) ates of general structure PhCH2OCONHCH (R) COCHR'(CH2) n (O) P (O2-)(O) R''(R= H, CH3; R'= H, CH3; n= 0, 1; R''= H, CH3, Et, Ph) have been prepared as a potential source of β-lactamase inhibitors. The phosphonates (n= 0)