A general method for the stereoselective conversion of homoallylic alcohols to erythro-or threo-β-hydroxy-α-amino acids is described. The key step is the stereoselective mercuric ion- initiated cyclofunctionalization of acylaminomethyl ether derivatives of the homoallylic alcohols (3→ 8). The stereochemistry of the products obtained from the cyclofunctionalization is controlled by the choice of reaction conditions. Reaction under ...
