Synthesis

A simple and effective synthesis of benzolactones and benzolactams by noncatalytic benzylic oxidation of cyclic benzylic ethers and N-protected cyclic benzylic …

AR Song, J Yu, C Zhang

Index: Song, Ai-Ru; Yu, Jun; Zhang, Chi Synthesis (Germany), 2012 , vol. 44, # 18 p. 2903 - 2909

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Citation Number: 3

Abstract

Abstract Sodium chlorite (NaClO 2) was shown to be capable of oxidizing cyclic benzylic ethers and N-protected cyclic benzylic amines in a heterogeneous solvent system of 1, 1, 1- trichloroethane and water at 55–65 C to give synthetically useful benzolactones and