MAOS of Quinoxalines, Conjugated Pyrazolylquinoxalines and Fused Pyrazoloquinoxalines from l??Ascorbic and d??Isoascorbic Acid

ESH El Ashry, KF Atta, S Aboul??Ela…

Index: Ashry, El Sayed H. El; Atta, Kamal F.; Aboul-Ela, Salah; Beldi, Razika Journal of Carbohydrate Chemistry, 2007 , vol. 26, # 1 p. 1 - 16

Full Text: HTML

Citation Number: 12

Abstract

Microwave??assisted organic synthesis (MAOS) has been used to accelerate the conversion of l??ascorbic acid (1) and d??isoascorbic acid (2) to the title heterocycles by conversion to 3??(l?? threo??or d??erythro??glycerol??1??yl) quinoxaline??2??carboxylic acid o??aminoanilides (7 and 8), which were transformed to lactones 9 and 10, respectively, under acidic condition. The acetylation of compounds 9 and 10 afforded 3??(l??threo??or d??erythro??2, 3??di??O??acetyl?? ...