Synthetic Communications

Free Radical–Mediated Chemoselective Reduction of Enones

A Sultan, AR Raza, MN Tahir

Index: Sultan, Aeysha; Raza, Abdul Rauf; Tahir, Muhammad Nawaz Synthetic Communications, 2014 , vol. 44, # 2 p. 267 - 274

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Citation Number: 2

Abstract

A novel methodology has been devised for the chemoselective reduction of enones involving the use of n Bu 3 SnH and azobisisobutyronitrile. The 1,4-reduction of variously substituted α,β-unsaturated cyclic and acyclic enones has been successfully carried out under free radical reaction conditions. The reaction has been determined to proceed via single-electron transfer. ... [Supplementary materials are available for this article. Go to the publisher's ...