Tetrahedron letters

A simple synthesis of some cyclic and acyclic cyclobutenediones

LS Liebeskind, SL Baysdon

Index: Liebeskind, Lanny S.; Baysdon, Sherrol L. Tetrahedron Letters, 1984 , vol. 25, # 17 p. 1747 - 1750

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Citation Number: 23

Abstract

The procedure of reference 16 was generally followed with the exception that POCl 3 was not used: 3a from 1.1 eq Cl 3 CCOCl in Et 2 O at rt for 16h - unstable to purification; 3b from 1.1 eq Cl 3 CCOCl in Et 2 O at reflux for 16h; 3c from 2 eq Cl 3 CCOCl in Et 2 O at reflux for 12h; 3d from 1.2 eq Cl 3 CCOCl in Et 2 O at rt for 8h. ... 4a: 1 eq Et 3 N then 1 eq PhSH added to crude 3a in CH 3 CN at 0° then warmed to rt, 2h; 4b: 1 eq Et 3 N added to 3b in CH 3 CN at 0° ...