Synthesis of alkyl and acyl derivatives N-formyl-α-alanine ethyl ester

ZI Itov, SD L'vova, VI Gunar, AR Bekker

Index: Itov,Z.I. et al. Pharmaceutical Chemistry Journal, 1977 , vol. 11, # 5 p. 646 - 649 Khimiko-Farmatsevticheskii Zhurnal, 1977 , vol. 11, # 5 p. 62 - 66

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Abstract

Compound I, as well as other formamides, exhibits a dual character, ie, its alkylation and acylation can occur at two different centers depending on the reaction conditions; either the nitrogen atom or the o~'gen atom can react. Usually, for N-alkylation of substituted amides