Three members of the cannabinoid class, cannabinol, cannabinol methyl ether, and cannabinodiol, were synthesized using a microwave-mediated [2+ 2+ 2] cyclotrimerization reaction as the key step. This approach provides a high level of synthetic flexibility allowing for the facile synthesis of cannabinoid analogues.
![1-hydroxy-9-methyl-3-pentyl-6H-dibenzo[b,d]pyran-6-one Structure](https://image.chemsrc.com/caspic/458/63839-83-8.png)
![2-[2-(2-hydroxypropan-2-yl)-5-methylphenyl]-5-pentylbenzene-1,3-diol Structure](https://image.chemsrc.com/caspic/496/63839-82-7.png)
