7996 2009 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim Angew. Chem. Int. Ed. 2009, 48, 7996–8000 g-Rubromycin [1](1, Scheme 1), the prototypical member of a structurally related family of antibiotics known as the rubromycins, consists of a densely oxygenated